I. Publizierte Arbeiten / Published studies:

198. Daha L., Riedl C.R., Hohlbrugger G., Knoll M., Engelhardt P., Pflüger H.:
     „Comparative assessment of maximal bladder capacity, 0.9% NaCl versus 0.2 KCl, for the diagnosis of interstitial cystitis: a prospective controlled study”
     PURPOSE: Increased urothelial permeability has been proposed as a cause of interstitial cystitis (IC). The potassium sensitivity test assesses bladder discomfort after instillation of 0.4 M KCl for identification of increased urothelial permeability. Since exposure to 0.4 M KCl may be extremely painful for patients with IC we investigated a less traumatic alternative. MATERIALS AND METHODS: The study comprised 38 controls and 40 patients with IC. In all subjects cystometry was performed with 0.9% NaCl followed by 0.2 M KCl, and filling volume at first urge and maximum bladder capacity (Cmax) were assessed for both solutions. RESULTS: Controls did not show a significant change in Cmax. KCl decreased Cmax in 37 of 40 (92%) patients with IC with a mean decrease of 30%. The examination was painless in all controls and in 33 of 40 (82%) patients with IC, and was moderately painful in 7. CONCLUSIONS: For demonstration of increased potassium sensitivity and diagnosis of IC, comparative assessment of Cmax is a well tolerated alternative to the 0.4 M potassium sensitivity test. Statistical evaluation of these results suggests that a decrease in Cmax greater than 30% is indicative of IC.
     J.Urol., 170, 807-809, 2003

     

199. Engelhard P., Daha L., Zils T., Simak R., König K., Pflüger H.:
     „Acupuncture in the treatment of psychogenic erectile dysfunction: first results of prospective randomised placebo-controlled study”
     In a prospective study, we investigated the potentially curative effect of acupuncture in patients with psychogenic erectile dysfunction (pED). A total of 22 patients with pED were randomized into two groups. They were either treated with acupuncture specific against ED (treatment group) or acupuncture specific against headache (placebo group). Nonresponders of the placebo group were crossed over to the treatment group. Prior to acupuncture, serum sexual hormone levels, IIEF score, nocturnal penile tumescence testing for three nights (Rigiscan) and the erectile response to 50 mg sildenafil were evaluated. Out of 21 patients, 20 completed the study, including 10 patients after crossover. A satisfactory response was achieved in 68.4% of the treatment group and in 9% of the placebo group (P=0.0017). Another 21.05% of the patients had improved erections, that is, sufficient rigidity under simultaneous treatment with 50 gm sildenafil. The results of our pilot study indicate that acupuncture can be an effective treatment option in more than two-thirds of patients with psychogenic erectile dysfunction.
     Int.J.Impotence Research, 15, 343-346, 2003

     

200. Daha L., Plas E. :
     ”Epidemiology and symptomatology of the aging bladder”
     in: E. Plas, WA. Hübner, U. Maier, H. Pflüger: Buch “The Aging Bladder”, (21- 30),
     Springer, 2003

     

201. E. Plas, LK. Daha:
     ”Hormonal Replacement Therapy for the Aging Bladder”
     in: E. Plas, WA. Hübner, U. Maier, H. Pflüger: Buch “The Aging Bladder”, (137-154),
     Springer, 2003

     

202. C. Hampel, E. Plas, LK Daha, JW Thüroff:
     ”Pathophysiology orientated therapy of the aging bladder” 
     in: E. Plas, WA. Hübner, U. Maier, H. Pflüger: Buch “The Aging Bladder”, (127-136),
     Springer, 2003

     

203. Pernkopf D., Plas, E. Treu T., Pflüger H.:
     „Harnfluss-Volumen Nomogramme für gesunde junge Männer – Das Van Swieten Nomogramm“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 72, 2003

     

204. Daha L., Riedl C.R., Lazar, D., Hohlbrugger G., Pflüger H.:
     „Komparative Feststellung der maximalen Blasenkapazität, 0,9% NaCl vs. 0,2 mol KCl, für die Therapie von interstitieller Zystitis: Vorläufige Daten“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 87, 2003

     

205. Witkowski M., Langmann F., Plas E., Pflüger H.:
     „Klangspektrografische ESWL-Analyse“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 89, 2003

     

206. Langmann F., Plas E., Pflüger H.:
     „Langzeitergebnisse der Iontophoresetherapie bei Induratio Penis Plastica (IPP)“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 94, 2003

     

207. Gallistl H., Plas E., Pflüger H.:
     „Testosteronbestimmung beim alternden Mann – wie viele Proben brauchen wir?“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 110, 2003

     

208. Untergasser G., Gander R., Heinrich E., Plas E., Berger P.:
     „Differenzierung und zelluläre Seneszenz des proliferativen Basal/Stamm Zellkompartiments der humanen Prostata. Ein Modellsystem für funktionelle Untersuchungen potentieller Tumorsuppressorgene“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 158, 2003

     

209. aniltchenko D., Riedl C., König F., Pflüger H., Loenig S.A.:
     „Senkung der Residualtumorrate des oberflächlichen Blasenkarzinoms durch ALA-Fluoreszenzzystoskopie: Ergebnisse einer prospektiv randomisierten 2-Center-Studie“
     W.Klin.Wochenschrift, Suppl.1, 115, Abstr. 165, 2003

     

210. Schmidt P.R., Pflüger H.:
     „Steinerkrankungen – ein Überblick, Diagnostik und Therapie“
     Der Hausarzt 1-2, 6-8, 2003

     

211. Daha L., Pflüger H.:
     „Interstitielle Cystitis“
     Facharzt Gynäkologie/Urologie, 4, 6-8, 2003

     

212. Pflüger H.:
     „Der alternde Mensch: Pro-Aging statt Anti-Aging“
     Urologik, 5, 26-27, 2003

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